Ozone is a safe, inexpensive, and effective clinical tool\nwith a wide range of therapeutic applications. Pain management is an area where\nozone excels, and many studies have been done to demonstrate its analgesic\nproperties. Numerous clinical trials and research studies have been conducted\nto investigate the effects of ozone therapy. Ozone has been shown to be\nbeneficial for a wide range of conditions, including pain, cardiovascular\ndisease, mitochondrial dysfunction, infection, and non-healing skin lesions.\nClinical practice has also shown benefit in neurological disorders,\nautoimmunity, fatigue, and others. The discussion of ozone in this article will\nbe limited to the area of pain. For a comprehensive overview of ozone therapy,\nPrinciples and Applications of Ozone Therapy \u2013 A Practical Guide for\nPhysicians, by Frank Shallenberger MD, is an excellent resource.<\/p>\n\n\n\n
Ozone can be administered in numerous ways. For the purpose\nof treating acute and chronic pain, ozone is traditionally administered as an\ninjection (often referred to as a \u201cprolozone\u201d). Patients suffering from chronic\npain of a systemic origin (e.g., fibromyalgia, chronic Lyme\/coinfections,\nCFIDS, environmental illness, etc.) may require similar injection therapies\nand\/or intravenous (IV) administration of ozone.<\/p>\n\n\n\n
OZONE ADMINISTRATION<\/p>\n\n\n\n
Intravenous administration of ozone is traditionally\nadministered as major autohemotherapy (MAH). MAH involves removing 60 to 250 mL\nof venous blood into an IV bag, mixing it with ozone gas, and a small amount of\nheparin (to prevent clotting). It is then re-infused into the patient. Unlike\nlocal injections, MAH provides a system-wide exposure to the effects of ozone,\nhence its applicability to systemic diseases, as mentioned above. Ozone can\nalso be administered to the whole body through IV ozonated-saturated saline,\nrectal insufflations of ozone gas, or cutaneous absorption via cupping or limb\nbagging.<\/p>\n\n\n\n
<\/p>\n\n\n\n